Laboratory for Chemistry and Life Science Institute of Innovative Research TOKYO INSTITUTE OF TECHNOLOGY

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  • Activity of Each Group

Molecular synthesis

Osakada-Koizumi Group

Osakada-Koizumi Group

Synthesis, structures, and properties of new materials composed of molecules or assembled molucules are investigated on the basis of inorganic and organic chemistry. Development and control of novel polymerization and oligomerization reactions have been investigated by design of transition metal complex catalysts and functionalized monomers.
Member
Prof. Kohtaro OSAKADA
Assoc. Prof. Take-aki KOIZUMI
Asst. Prof. Yoshitaka TSUCHIDO

WEBSITE

Latest Research
2017.12
Synthesis of Optically Active Polystyrene by Asymmetric Polymerization of Styrene Catalyzed by Monophosphine Pd Complexes

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Molecular synthesis

Akita-Yoshizawa Group

Development of Smart Chemical Systems

Akita-Yoshizawa Group

Our research interests focus on the development of novel smart molecules by the use of pi-conjugated organic units and metal ions. We believe the molecules, methods, and concepts developed in our laboratory will have wide ranging applications for functional materials and practical catalytic reactions.

Member
Prof. Munetaka AKITA
Assoc. Prof. Michito YOSHIZAWA
Asst. Prof. Takashi KOIKE
Asst. Prof. Yuya TANAKA

WEBSITE

Latest Research
2017.08
How to Make "Molecular Peanuts"

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Molecular synthesis

Nakamura-Fuse Group

Exploring and Controlling Vital Function Using Designed Synthetic Molecules for Innovative Drug Discovery

Nakamura-Fuse Group

Our research interests are focused on discovery of drug candidates for anticancer agents, development of new methodologies for target protein-selective modification in chemical biology, and development of efficient boron delivery system in neutron capture therapy of cancer. Our research is directed to interdisciplinary area based on organic synthetic technology to explore and control vital function for innovative drug discovery.

Member
Prof. Hiroyuki NAKAMURA
Assoc. Prof. Shinichiro FUSE
Asst. Prof. Shinichi SATO

WEBSITE

Latest Research
2017.04
HRP-Catalyzed Tyrosine Click Reaction with Luminol Derivatives

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Molecular materials design

Fukushima-Shoji Group

Inovative Functional Materials by Advanced Molecular Science

Fukushima-Shoji Group

Our research interest is directed toward the development of novel molecular-based materials by taking full advantage of multi-disciplinary research fields including organic, organometallic, polymer, and supramolecular chemistry. We design new functional molecular building blocks that exhibit electronic, optoelectronic, and even dynamic properties. We also develop methodologies to achieve controlled self-assembly of the functional molecules into well-defined molecular objects with a high structural precision from nano to macroscopic length scales. Through the works, we intend to establish new design concepts for innovative functions.

Member
Prof. Takanori FUKUSHIMA
Assoc. Prof. Yoshiaki SHOJI
Assoc. Prof. Takashi KAJITANI
Asst. Prof. Fumitaka ISHIWARI

WEBSITE

Latest Research
2017.09
Novel boron-mediated benzannulation reaction of alkynes enabling the facile synthesis of extended π-conjugated systems

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Molecular materials design

Nishiyama Group

Nishiyama Group

In our laboratory, we have studied the new concept of drug development based on fine-tuning synthetic polymers. We integrate the targeting functionality, stimuli-responsive functionality and drug conjugating functionality into the platform of synthetic polymers, thereby aiming to realize smart medicine. Our targets include realization of effective but non-toxic cancer treatment, practical use of emerging biomedicine, biofunctional imaging, and minimally invasive surgery in combination with medical instruments.

Member
Prof. Nobuhiro NISHIYAMA
Asst. Hiroyasu TAKEMOTO
Asst. Takahiro NOMOTO
Asst. Makoto MATSUI

WEBSITE

Latest Research
2018.06
Construction of ethylenediamine-based polyzwitterion for effective accumulation of the coated nanomaterials in tumor

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Molecular materials design

Nagai Group

Photoenergy Conversion Materials

Nagai Group

We produce environmental friendly Photoenergy Conversion Materials.
Low density controlled shape materials are efficient target from high power laser to quantum beam. For high repetitive laser (10- 100kHz), mass productive synthesis, and target derivering system is also required.
Organic semiconductors gave full-spectrum visible light responsive photocatalyst to split water to H2 + O2. Volatile organic compounds are decomposed to CO2 with high quantum yield.

Member
Assoc. Prof. Keiji NAGAI

WEBSITE

Latest Research
2018.03
Low Density Porous Materials for Laser Plasma Generation

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Molecular materials design

Shishido Group

Emergence of new functions by molecular alignment control

Shishido Group

We focus on fundamental understanding of the interaction between light and polymer materials from the viewpoint of innovative photonic applications, and create photofunctional polymer materials with precisely controlled molecular alignment.

Member
Prof. Atsushi SHISHIDO
Asst.Prof. Norihisa AKAMATSU

WEBSITE

Latest Research
2017.05
Photo-Polymerization Induces Two-Dimensional Molecular Orientation without Polarized Light or Dye Molecule

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Molecular materials design

Nomura Group

Nomura Group

Development of environmentally benign processes through the innovation in microporous and mesoporous materials, energy transformation by photocatalytic decomposition of water, development of novel functional materials, and reaction dynamics on solid surface.

Member
Assoc. Prof. Junko NOMURA

WEBSITE

Latest Research
2018.03
Elucidation of zeolite acidity and proton hopping mechanism at high temperature using infrared spectroscopy

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Molecular functions

Fujii-Ishiuchi Group

Laser spectroscopy of molecules and molecular clusters,
and development of new laser spectroscopic technique

Fujii-Ishiuchi Group

1) Structures and dynamics of chemically important molecules and molecular clusters in excited states and ionic states.
2) Chemical reaction dynamics studied by time-resolved spectroscopy
3) Gas phase spectroscopy of biomolecules in terms of understanding molecular recognition mechanism and photoexcitation dynamics
4) Application of laser spectroscopy to analysis of material and environment
5) Development of novel microscope and micro-spectroscopy

Member
Prof. Masaaki FUJII
Assoc. Prof. Shun-ichi ISHIUCHI
Asst. Prof. Mitsuhiko MIYAZAKI

WEBSITE

Latest Research
2017.03
Gas-phase spectroscopy of complexes of noradrenaline and alkali metal ions by using electrospray cryogenic ion trap technique

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Molecular functions

Yamamoto-Imaoka Group

Hybrid Chemistry Based on Atomic-level Programming for Advanced Metallo-nanomaterials

Yamamoto-Imaoka Group

Metal-organic hybrid nanomaterials have a limitless potential for synergistic functions like metalloproteins, because the organic frameworks have a significant diversity for design and synthesis and there are almost 110 inorganic elements as a substrates. However, we cannot yet freely assemble and hybridize their elements at the atomic level. The methodology for building fine-controlled nanostructures using the large variety of inorganic elements as raw materials will surely lead to the generation of yet unknown next-generation functional nano-materials. That is, the approach through "Advanced Inorganic Chemistry Based on Atomic-level Programming" is one of the most important general strategy for the next-generation nanotechnology.
Our research aims to explore the methodology for the design and construction of fine-controlled hybrid materials through "Advanced Inorganic Chemistry Based on Atomic-level Programming", in which the chemical bonds and arrangements of metal atoms and ions are reversibly and precisely controlled. Our group is also striving to open up new field to create innovative future nano-materials, which will have an impact on the environmental, biomimetic, and energy sciences.

Member
Prof. Kimihisa YAMAMOTO
Assoc. Prof. Takane IMAOKA
Asst. Prof. Ken ALBRECHT(YAMASHITA)
Asst. Prof. Tetsuya KANBE

WEBSITE

Latest Research
2017.07
Polymerization of Atom-Mimicking Dendrimer

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Molecular functions

Yamaguchi-Tamaki Group

Yamaguchi-Tamaki Group

The theme is the construction of the design method of chemical process systems from the viewpoint of the environment, energy and resources.

Member
Prof. Takeo YAMAGUCHI
Assoc. Prof. Takanori TAMAKI
Asst. Prof. Yuhei OSHIBA
Asst. Prof. Yuuki SUGAWARA
Asst. Prof. Shoji MIYANISHI

WEBSITE

Latest Research
2018.02
High-sensitive Molecular Detection Using Biomolecule-Recognition Gating Membrane with Small Pore Space for Disease Diagnostics

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Molecular bioscience

Tanaka-Imamura Group

Tanaka-Imamura Group

Molecular cell biology for both prokaryotes and eukaryotes, which focuses on the regulatory aspects of cellular growth and metabolism.

Member
Prof. Kan TANAKA
Assoc. Prof. Sousuke IMAMURA
Asst. Prof. Yuki KOBAYASHI

WEBSITE

Latest Research
2018.05
Target of rapamycin: linking chloroplast and cytosolic ribosome biogenesis in plants

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Molecular bioscience

Ueda-Kitaguchi Group

Development of novel biosensors and analytical methods by protein engineering and chemical biology

Ueda-Kitaguchi Group

In nature, many proteins exhibit high performances such as molecular recognition ability and catalytic activity, which are still difficult to emulate artificially. However, natural protein does not always have ideal property from the viewpoint of application to the continuous development of human society. That is why we aim at creating novel proteins with superior performances and the assays using them, through the rational design and molecular evolution, as well as chemical biological techniques.

Member
Prof. Hiroshi UEDA
Assoc. Prof. Tetsuya KITAGUCHI
Asst. Prof. Hiroyuki TANAKA
Asst. Prof. Yuki OHMURO

WEBSITE

Latest Research
2017.10
Tailor-made biosensor to color the molecular world

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Molecular bioscience

Hisabori-Wakabayashi Group

Hisabori-Wakabayashi Group

Our research group try to understand the regulatory mechanism of the energy conversion apparatus in the photosynthetic organisms. They are the most important organisms as an energy resource on the earth since they directly convert the solar energy to the chemical energy. We study the new way for the application of the capability of the various enzyme function of the microbes as well.

Member
Prof. Toru HISABORI
Assoc. Prof. Ken-ichi WAKABAYASHI
Asst. Prof. Jiro NOMATA
Asst. Prof. Keisuke YOSHIDA

WEBSITE

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CORE Group

Visiting Researchers Group

Member
Assoc. Prof. Shigenori FUJIKAWA

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